Juventus' miserable start to the Serie A season continued as it lost 2-1 at Napoli, while Roma reignited its league campaign with a 5-1 drubbing of newly-promoted Carpi on Saturday.

Lorenzo Insigne and Gonzalo Higuain scored for Napoli before Mario Lemina pulled one back.

It was the four-time defending champion's third defeat in its first six league matches this season. Juventus lost just three all season last year, while it had only two defeats the previous campaign.

Juventus is already 10 points behind early leader Inter Milan, which hosts Fiorentina on Sunday. Napoli moved provisionally seventh with its second win of the season.

Roma coach Rudi Garcia was also under pressure after picking up just one point in two matches against Sassuolo and Sampdoria.

But his side responded with goals from Kostas Manolas, Miralem Pjanic, Gervinho, Mohamed Salah and Lucas Digne.

Gervinho, who hadn't scored in nearly a year, also hit the post.

Marco Borriello scored against his old club for Carpi, which also had Ryder Matos' penalty saved by Morgan De Sanctis.

The only sour note for Roma was Edin Dzeko spraining his knee while Francesco Totti and Seydou Keita also went off injured.

Roma moved provisionally third ahead of Sunday's fixtures.

Juventus was without Stephan Lichtsteiner, Claudio Marchisio, Mario Mandzukic and Sami Khedira, while Alvaro Morata and Juan Cuadrado were rested ahead of Wednesday's home Champions League match against Sevilla.

Inisgne was making his 100th appearance for Napoli and he marked the occasion with a goal, playing a neat one-two with Higuain before firing into the bottom left corner to hand his side a 26th-minute lead.

He pulled up with a knee problem later in the half and had to be replaced shortly before the interval.

Higuain got on the scoresheet himself shortly after the hour mark. Hernanes gave the ball away just inside his own half, passing straight to Higuain and the Argentina forwad went on a mazy run downfield before firing across Gianluigi Buffon, who got a hand to it but the finish was too powerful.

It was Higuain's seventh goal in as many matches.

Juventus got one back almost immediately as less than a minute later Lemina was left relatively unmarked at the far post to slot Paulo Dybala's cross into the bottom right corner.

Roma was looking for a win to push its way back up the table and also boost confidence ahead of Tuesday's trio to BATE Borisov in the Champions League.

Manolas had scored an own goal in Wednesday's 2-1 defeat at Sampdoria and he scored at the right end in the 24th minute, controlling Digne's wayward effort before turning and firing in his first goal for the club.

Pjanic doubled Roma's advantage four minuutes later with a delightful free kick over the wall and into the bottom left corner.

And Roma went 3-0 up in the 31st when Zeljko Brkic could only parry Douglas Maicon's shot and Gervinho turned in the rebound for his first goal since November.

Borriello had been denied earlier by a De Sanctis save, but he got one back for Carpi in the 34th, heading in Gabriel Silva's cross.

Totti came on at halftime and immediately set up a goal for Roma with a chipped effort which Brkic pushed clear and Salah scored on the rebound.

However, Totti had hurt his thigh in that move and was immediately replaced.

Digne also scored his first goal for Roma in the 68th, when he was left unmarked to head in Maicon's cross.

Carpi could have had a consolation goal when it was awarded a soft penalty in the 76th minute when Maicon was adjudged to have pushed over Antonio Di Gaudio, but De Sanctis pulled off a fantastic double save to stop the penalty and the follow-up by Matos.