POPE

MEXICO CITY — Pope Francis wraps up his trip to Mexico on Wednesday with some of his most anticipated events: a visit in a Juarez prison just days after a deadly riot in another lockup and a stop at the Texas border when immigration is a hot issue in the U.S. presidential campaign. 

OBAMA-ASEAN

RANCHO MIRAGE, California — President Barack Obama and the leaders of Southeast Asia call for peaceful resolution of the region's maritime disputes as they conclude a summit in California. 

SUPREME COURT-POLITICS

RANCHO MIRAGE, California — President Barack Obama declares that Republicans have no constitutional grounds to refuse to vote on a Supreme Court nominee, and he challenges his political foes in the Senate to rise above the "venom and rancor" that has paralyzed judicial nominations.

PRESIDENTIAL RACE

CHARLESTON, South Carolina — Jeb Bush, John Kasich and Marco Rubio are locked in a high-stakes political chess match in South Carolina, strategically moving money and other campaign resources around in a bid to pull ahead in the Republican primary race — or at least keep their campaigns afloat if they don't.

CUBA-US FLIGHTS

HAVANA — The United States and Cuba sign a deal restoring commercial air traffic for the first time in five decades, allowing dozens of new daily flights to bring hundreds of thousands more American travelers a year to the island as early as this fall. 

CALIFORNIA SHOOTINGS

WASHINGTON — A U.S. magistrate orders Apple Inc. to help the Obama administration hack into an encrypted iPhone belonging to one of the shooters in the December attack in San Bernardino, California, that killed 14 people, in a first-of-its-kind ruling that pits digital privacy against national security interests. 

UNITED STATES-SYRIA

WASHINGTON — The Obama administration, frustrated by Syria's ongoing violence, tells Russia to "put up or shut up" about implementing a ceasefire in the Arab country, even as the U.S. backpedaled from an agreement for the truce to begin by Friday. 

ZIKA-MOSQUITOES

GENEVA — The World Health Organization says it may be necessary to use controversial methods like genetically modified mosquitoes to wipe out the insects that are spreading the Zika virus across the Americas.