Marco Reus and Robert Lewandowski scored twice each for Borussia Dortmund to rout 10-man Freiburg 5-0, while Bayern Munich labored past Wolfsburg 1-0 in the Bundesliga on Saturday.
Bayer Leverkusen beat Hannover 2-0 as the trio of leaders opened a significant gap seven games into the season.
Dortmund leads on goal difference over Bayern. Leverkusen was a point behind them, six ahead of Hannover.
In other matches, Hoffenheim rallied from a two-goal deficit to draw 3-3 with Schalke, and Hertha also came from behind to beat Mainz 3-1. Mainz lost its fourth straight.
In the late match, Eintracht Frankfurt hosted Hamburger SV.
Wolfsburg's run of futility in Munich extended to 17 matches — the visitors have never won at Bayern and earned only one draw.
Wolfsburg massed its defense and Pep Guardiola's team struggled to find openings.
In a game with few highlights, it was substitute Xherdan Shaqiri who launched Bayern's scoring move with his first action of the match. Shaquiri released Franck Ribery and Thomas Mueller knocked in his cross at the far post in the 63rd. It was Mueller's third goal in two games, after he notched two in the midweek 4-1 win over Hannover in the German Cup.
Dortmund had a much easier time at home against still winless Freiburg, which lost defender Fallou Diagne to a red card in the 45th for a last-man foul on Lewandowski.
Freiburg goalkeeper Oliver Baumann parried a long-range shot, Lewandowski pounced on the rebound, Baumann blocked again but Reus was there to lift the ball over the goalie for Dortmund's lead in the 35th.
Reus converted the penalty after Diagne's foul to double the lead.
Reus supplied the pass for Lewandowski's first goal. The striker shook off two defenders and chipped the ball over Baumann.
Lewandowski made it 4-0 with his sixth goal of the season, connecting with a square pass at the far post. Jakub Blaszczykowski completed the scoring in the 79th.
In Leverkusen, Sidney Sam and Simon Rolfes combined to secure Leverkusen's victory. With six wins in seven games, Leverkusen is off to the best start in the club's history. Leverkusen next plays Bayern.
Sam sent a free kick into the box and Rolfes rose to head home in the 23rd, before Sam slotted home after a through ball from Rolfes in the 37th.
The most entertaining match was Hoffenheim's comeback against Schalke. Schalke has never won at Hoffenheim and stayed true to the tradition despite a 3-1 lead.
Kevin-Prince Boateng scored in the third minute for Schalke, firing home from the middle of the box after an inside pass form Max Meyer.
Joel Maltip headed in a free kick from Jefferson Farfan 10 minutes later to double the lead, before a mistake by Schalke's defense allowed Athony Modest to cut the deficit with his sixth goal of the season.
Marco Hoeger's solo run produced Schalke's third in the 40th.
Dennis Aogo, who had released Hoeger, tripped Kevin Volland to give away a penalty in the 48th and Roberto Firmino converted to start Hoffenheim's comeback.
The equalizer came when David Ambraham drilled the ball over the wall with a free kick in the 61st and Firmino hit the underside of the crossbar late in the match as Hoffenheim nearly won the match.
In Berlin, promoted Hertha fell behind to an early goal by Nicolai Mueller, his sixth of the season, before substitute Sami Allagui scored twice in the second half and Anis Ben-Hatira completed the comeback.