Holders Balzan were yesterday drawn to meet Second Division side San Gwann when the draws were made yesterday at the Trophies Lounge in the Millennium Stand at the National Stadium.
In last season's final, Balzan had defeated Valletta on penalties after a highly entertaining and well contested match which had ended 4-4 after 90 minutes.
There are three all Premier club matches in the third round draw. These are Gzira-Senglea, Sliema-Santa Lucia and Tarxien R.-Hamrun S.
The top six clubs in last year's Premier League were all seeded in the third round draw. These were Balzan, Hibernians, Gzira, Valletta, Sliema and Hamrun.
Apart from the six seeded clubs all the others taking part in this season's Premier League - Birkirkara, Floriana, Gudja, Mosta, Santa Lucia, Senglea, Sirens and Tarxien R. - are also included.
The remaining teams from the smaller divisions who advanced from the first and second rounds are first division sides Lija Athletic, Mqabba, Pembroke Athleta, Pieta H., Qormi, St Andrews, Swieqi U., Zebbug R. and Zejtun Corinthians.
Teams remaining from the second division are Melita, Mgarr U., Rabat Ajax, San Gwann and Zabbar St Patrick. No teams hail from the third division, but four clubs from the Gozo Football Association also advanced to the third round draw. These are Kercem A, Nadur Y., Victoria H. and Xewkija T.
3rd round draw
Balzan-San Gwann
Zejtun-Hibernians
Gzira U.-Senglea
St Andrews-Valletta
Sliema-Santa Lucia
Tarxien R.-Hamrun S.
Kercem A.-Sirens
Floriana-Melita
Qormi-Swieqi U.
Rabat-Mosta
Pembroke-Zabbar SP
Birkirkara-Nadur Y.
Zebbug R.-Victoria H.
Gudja-Lija Ath.
Mqabba-Pieta H.
Xewkija T.-Mgarr U.
4th round draw
Qormi/Swieqi v Tarxien/Hamrun
Balzan/San Gwann v Sliema/Sta Lucia
Pembroke/Zabbar SP v Zejtun/Hibernians
Zebbug/Victoria H./Gudja/Lija A.
Mqabba/Pieta v Xewkija/Mgarr
Floriana/Melita v Gzira/Senglea
St Andrews/Valletta v Kercem A./Sirens
Rabat/Mosta v Birkirkara/Nadur
The third round is to be played during the weekend between Friday 29 November and Sunday 1 December.
The eight 4th round matches are scheduled for Friday 24, Saturday 25 and Sunday 26 January 2020.