Serie B champion Lecce won at Salernitana 2-1 on Friday for its first victory since returning to the top division.
Gabriel Strefezza scored the winner from beyond the area following a counterattack in the 83rd minute of the all-southern matchup.
Salernitana, coming off a 2-2 draw at Juventus, equalized when Lecce midfielder Joan Gonzàlez redirected a corner into his own net.
Gambia forward Assan Ceesay put Lecce ahead on a counterattack that he finished off by dribbling around the goalkeeper and slotting into an empty net from a sharp angle.
Salernitana remained 10th while Lecce moved up to 14th.