AC Milan host Arsenal in the last 16 of the Europa League on Thursday evening, and will be hoping to capitalize on their poor run of form and put one foot into the quarterfinals of the competition.

In contrast to Arsenal, AC Milan are on fine form. They are unbeaten in their last six games, and will be full of confidence going into this home tie.

Meanwhile, Arsenal have lost each of their last four games, the first time they have succumbed to that many consecutive defeats since Arsene Wenger joined the club in 1996.

Arsenal manager Arsene Wenger gestures during the English Premier League soccer match between Arsenal and Manchester City at the Emirates stadium in London, Thursday, March 1, 2018.(AP Photo/Frank Augstein)

Classic Encounter

Milan romped to a 4-0 victory when they hosted Arsenal back in 2012. Kevin-Prince Boateng struck to give Milan the lead, before a double from Robinho saw Milan find themselves 3-0 up and Arsenal's European hopes were left in tatters.

Zlatan Ibrahimovic added insult to injury from the penalty, inflicting one of Arsenal's heaviest European defeats ever.

AC Milan's Alessio Romagnoli scores the decisive penalty during the Italian Cup, second-leg semifinal soccer match between Lazio and AC Milan, at the Rome Olympic stadium Wednesday, Feb. 28, 2018. AC Milan won 5-4 following a penalty shootout and advances to the final where it plays Juventus. (Ettore Ferrari/ANSA via AP)

In the second leg in North London, Arsenal looked on course for a stunning comeback as they fired home three first-half goals to reduce the aggregate score to 4-3.

Goals from Laurent Koscielny and Tomas Rosicky, and a Robin van Persie penalty, saw the Gunners go into the break 3-0 ahead on the night. However, they couldn't manage to add to their tally in the second half and were knocked out of the competition by a 4-3 aggregate scoreline.

AC Milan coach Gennaro Gattuso gives indications during the Italian Cup, second-leg semifinal soccer match between Lazio and AC Milan, at the Rome Olympic stadium Wednesday, Feb. 28, 2018. (Angelo Carconi/ANSA via AP)

Key Battles

Patrick Cutrone vs Laurent Koscielny

In-form Milan striker Patrick Cutrone is likely to lead the line for Milan. He will be looking to continue his European goal scoring run, having netted six times in 11 European games this season.

The 6ft 2in striker, who is still just 20-years-old, will face a stern test against Arsenal defender Laurent Koscielny. The experienced Frenchman has 50 caps for his country and has played for Arsenal on 317 occasions since joining in 2010.

AC Milan's Alessio Romagnoli, top left, celebrates with goalie Gianluigi Donnarumma and defender Leonardo Bonucci after scoring the decisive penalty during the Italian Cup, second-leg semifinal soccer match between Lazio and AC Milan, at the Rome Olympic stadium Wednesday, Feb. 28, 2018. AC Milan won 5-4 following a penalty shootout and advances to the final where it plays Juventus. (Ettore Ferrari/ANSA via AP)

Mesut Özil vs Lucas Biglia

Arsenal will look to Özil to be their creative outlet in the centre of the park, as they look to control Milan's three-man midfield. The German international has a fantastic creative flair and can break defensive lines with ease, when his mind is in the right place.

Milan will look to counter him by playing Lucas Biglia in a holding midfield role, picking up Ozil's runs, intercepting passes between their defensive and midfield lines; and screening his back four.

Biglia has cemented his place in Milan's midfield, and executes this role well. It will make for an interesting battle on Thursday evening.

Arsenal's Pierre-Emerick Aubameyang, center, reacts after Manchester City scored their second goal during the English League Cup final soccer match between Arsenal and Manchester City at Wembley stadium in London, Sunday, Feb. 25, 2018. (AP Photo/Frank Augstein)

Team News

After resting some key players for the Premier League defeat at Brighton, Arsenal will return to full strength for this Europa League tie.

This will mean returns to the side for midfielder Aaron Ramsey.

However, Alexandre Lacazette, Pierre-Emerick Aubameyang and Nacho Monreal are all unavailable for Arsenal. 

Arsenal full back Hector Bellerin will miss Thursday’s Europa League game against AC Milan after picking up a knee injury in training, manager Arsene Wenger said on Wednesday.

Bellerin, 22, who was a late substitute in Arsenal’s 2-1 Premier League defeat by Brighton and Hove Albion last weekend, did not travel with the team to Italy for the first leg of the last-16 tie.

Sead Kolašinac could come in for Monreal, while Danny Welbeck is set to be given a chance up front.

Meanwhile, Milan will be without Luca Antonelli, Ignazio Abate and Andrea Conti through injury. They have all of their first choice players available, as they look to continue their winning run and deepen Arsenal's woes.